Azidothymidine (AZT) leads to arterial stiffening and intima-media thickening in mice
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چکیده
منابع مشابه
Increased arterial stiffening and thickening in the paretic lower limb in patients with hemiparesis.
Atherosclerosis has two key components, thickening and stiffening of arterial wall. These parameters are quantified ultrasonographically by IMT (intima-media thickness) and PWV (pulse wave velocity). In the present study, we determined the FA IMT (IMT of the bilateral femoral artery) and PWV of femoral-ankle (PWV fa) and brachial-ankle (PWV ba) segments in order to examine whether the degree of...
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15 صفحه اولCarotid wall viscosity increase is related to intima-media thickening in hypertensive patients.
Increases in arterial wall viscosity and intima-media thickness (IMT) were found in hypertensive patients. Because smooth muscle cells are responsible for the viscous behavior of the arterial wall and they are involved in the process of thickening of the intima-media complex, this study evaluates the relationship between carotid thickness and wall viscosity. The simultaneous and noninvasive ass...
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abstract introduction: hypertension is a very common cardiovascular disease with extensive effects on body organs. this study was conducted to compare the extent of target organ damage in hypertensive patients with and without significant nocturnal fall in blood pressure (dippers and non-dippers, respectively). methods: one-hundred patients with recently diagnosed hypertension underwent 24-hou...
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BACKGROUND Arterial stiffness (AS) is an independent risk factor for cardiovascular morbidity/mortality. Smooth muscle cell (SMC) proliferation and increased collagen synthesis are key features in development of AS. Arginase (ARG), an enzyme implicated in many cardiovascular diseases, can compete with nitric oxide (NO) synthase for their common substrate, L-arginine. Increased arginase can also...
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ژورنال
عنوان ژورنال: Journal of Biomechanics
سال: 2013
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2013.03.021